SELAM TADELE MARKOS2026-02-022023-11https://etd.hu.edu.et/handle/123456789/442Background: Neonatal hypoglycemia is one of the most common metabolic abnormalities seen in newborns. If unrecognized or poorly treated it may result in poor neurologic development, motor deficits, poor intellectual function, seizure disorders, or even death. In Ethiopia, neonatal hypoglycemia is frequently diagnosed and one of the commonest causes of admission to the neonatal intensive care unit. Nevertheless, documented records regarding its magnitude and factors associated with hypoglycemia are scarce in the study area. Objective: To assess the magnitude of neonatal hypoglycemia and its associated factors among neonates admitted to the neonatal intensive care unit at Hawassa City Public Hospitals, Ethiopia. Method: Institution-based cross-sectional study was conducted among 293 neonates admitted in Hawassa City Public Hospitals, Ethiopia from April 20 – June 20, 2023. The study participants were neonates with their mothers. A convenience sampling technique was used to reach the study subjects. A structured pretested questionnaire was adopted from different studies and the data was collected through face-to-face interviews and card review. Ethical clearance was taken from Hawassa University institutional review board and consent was taken from mothers of neonates. Then the collected data were checked, coded, and entered into Epi data version 3.1 and exported to SPSS software version 25 for cleaning and analysis. A Binary logistic regression model was used to determine the association. From bivariate analysis, variables with p-values <0.25 were taken for multivariable analysis. From multivariable analysis, variables with adjusted odds ratio, p-values <0.05 at 95% confidence interval (CI) were declared as factors significantly associated with neonatal hypoglycemia. Result: In this study, from all neonate-mother pair the overall response rate was 92.5%. The magnitude of neonatal hypoglycemia was found 16.6%. Variables significantly associated with the occurrence of neonatal hypoglycemia were: Diabetes mellitus [AOR=9.8, 95%CI (3.08 31.37)], perinatal asphyxia [AOR=2.87, 95%CI (1.07-7.72)], delayed initiation of breastfeeding [AOR=2.63, 95%CI (1.04-6.6)] and hypothermia [AOR=3.8, 95%CI (1.6-9.1)]. Conclusion: the magnitude of neonatal hypoglycemia among neonates was high. Neonates with hypothermia, perinatal asphyxia, and delayed initiation of breastfeeding and maternal history of diabetes mellitus have an increased risk of developing hypoglycemia. Hence, Health care providers who are working on delivery and neonatal care should focus on early identification and management of these identified factors.neonatediabetes mellitushypoglycemiaBlood glucoseThesis