Browsing by Author "ABATIHUN SHITIE"

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    PHYTOCHEMICAL INVESTIGATION OF THE STEM BARK OF STEREOSPERMUM KUNTHIANUM
    (Hawassa University, 2024-10) ABATIHUN SHITIE
    The traditional medicinal system continues to play an essential role in health care, with about 80% of the world’s inhabitants relying mainly on traditional medicines for their primary health care. The genus Stereospermum is known to possess medicinal properties in every part of the plant. Stereospermum kunthianum is one of the medicinal plants that has been claimed to be used traditionally to treat several illnesses such stomachaches, toothache, snake bitze, gonorrhea, evil eyes, diarrhea, skin diseases, and headaches. This study was conducted to investigate “Phytochemical constituents of stem bark of Stereospermum kunthianum”. The stem bark (500 g) of Stereospermum kunthianum was extracted with n-hexane, chloroform/methanol (v/v, 1:1) and methanol solvent systems sequentially using maceration technique and resulted in 1.8 g, 9.8 g and 15 g crude extract respectively. Phytochemical screening was carried out by standard procedures and the result showed the presence of the classes of secondary metabolites such as alkaloids, tannins, saponins, steroids, flavonoids, phenols, glycosides, and terpenoids.The chloroform/methanol (v/v, 1:1) crude extract was subjected to column chromatography that resulted in three compounds coded as SK1,SK2 and SK3. The structures of the isolated compounds was partially characterized by generating UV and IR data,systematically interpreting the data,melting point and comparing the data with literature.The FTIR analysis revealed that SK1, SK2 and SK3 are in good agreement with solanidanes, α-amyrin and Betulin respectively