Browsing by Author "ADISU NEGESA"

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    INCIDENCE AND PREDICTORS OF HYPOTENSION AFTER SPINAL ANESTHESIA AMONG PREECLAMPTIC MOTHERS WHO UNDERWENT CESAREAN SECTION IN SELECTED TEACHING HOSPITALS OF SOUTHERN ETHIOPIA, 2024: A MULTICENTER PROSPECTIVE COHORT STUDY
    (hawassa university, 2004-10) ADISU NEGESA
    Background: Preeclampsia is the most common cause of fetal and maternal problems in developing nations. The incidence of hypotension after spinal anesthesia in preeclamtic mothers during cesarean section ranges from 7-89%. In patients with severe preeclampsia, anesthesia professionals are frequently discouraged from using spinal anesthesia due to the risk of severe hypotension. Objectives: To assess the incidence and predictors of hypotension after spinal anesthesia among preeclamptic mothers who underwent cesarean section in selected teaching hospitals in southern Ethiopia. Methods and materials: A multicenter prospective cohort study was conducted among 140 mothers with preeclampsia in 6 randomly selected teaching hospitals in southern Ethiopia from February 1 to April 30, 2024. Data were entered into Epidata version 4.6 and exported into SPSS version 27 for analysis. The variables with a p-value of <0.25 in the bivariable logistic regression were inserted into the multivariable logistic regression. Multivariable logistic regression analysis identified the independent predictors of hypotension after spinal anesthesia. The degree of association was assessed using the Adjusted Odds Ratio (AOR) with a p-value of <0.05 being considered statistically significant. Results: The overall incidence of hypotension after spinal anesthesia was 50.7%. The dose of bupivacaine >10 mg (AOR=6.28, 95% CI; 1.96-20.06), spinal puncture to baby delivery duration >10 minutes (AOR=5.0, 95%CI; 1.48-16.86), estimated blood loss >500 ml (AOR=5.24, 95% CI; 1.12-24.46) and duration of surgery ≥40 minutes (AOR=5.81, 95% CI; 1.03-32.55) were identified predictors of hypotension after spinal anesthesia. Conclusion and recommendation: The incidence of hypotension after spinal anesthesia in mothers with preeclampsia was high. Therefore, professionals must use small doses of bupivacaine, reduce spinal puncture to baby delivery time, minimize blood loss, and decrease surgery duration since they are predictors of hypotension after spinal anesthesia.